L or hidden populations (Denzin Lincoln, 1994), although by contrast qualitative approaches have often been methodologically weak in procedures for “mixing” qualitative and quantitative methods and data and for processing their inductively derived information (verbal evidence; Dreher, 1994; Gelo et al., 2008; Plano Clark et al., 2008). These limitations include weaknesses in precisely describing interrelationships that exist among two or more of inductively generated 4-Deoxyuridine manufacturer constructs or categories. Although such associations can be explored using visual case-ordered and predictor-outcome matrix methods that allow a crosstabulation of categorical information (Miles Huberman, 1994), nonetheless, these methods have lacked the capacity to reliably assess the strength of association among keyJ Mix Methods Res. Author manuscript; available in PMC 2011 December 11.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptCastro et al.Pagecategories or constructs, as can be accomplished with quantitative methods such as correlational analyses.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptEven among mixed methods studies, a common limitation has been the use of qualitative and quantitative approaches in a sequential temporal order, thus limiting the integration of both data forms under a unified process of data analysis (Bryman, 2007). Typically, focus group information has been obtained during Stage 1 (e.g., a pilot study) to develop or refine instruments and procedures, followed by Stage 2 (e.g., the “core study”) in which survey or other quantitative data are then collected (Creswell, 1994). Unfortunately, few studies have effectively integrated qualitative and quantitative approaches under a unified and fully integrative research design and data analytic plan (Bryman, 2007; Dreher, 1994; Hanson, Creswell, Clark, Petska, Creswell, 2005). Based on a decade of our pilot research, the IMM approach, as presented here, has been designed for a concurrent, integrative, and unified analysis of qualitative and quantitative data. It aims to incorporate the strengths of qualitative and quantitative approaches for conducting rigorous data analyses that meet scientific standards of reliable and valid measurement and analysis. Mixed Methods Design Approaches Sequential mixed methods designs–Creswell, Plano Clark, Gutmann, and Hanson (2003) classified mixed methods designs into two major categories: sequential and concurrent. In sequential designs, either the qualitative or quantitative data are collected in an initial stage, followed by the collection of the other data type during a second stage. In contrast, concurrent designs are characterized by the collection of both types of data during the same stage. Within each of these two categories, there can be three specific designs based on (a) the level of emphasis given to the qualitative and quantitative data (equal or unequal), (b) the process used to Naramycin A site analyze and integrate the data, and (c) whether or not the theoretical basis underlying the study methodology is to bring about social change or advocacy (Creswell et al., 2003). In accord with this typology, the three types of sequential mixed methods designs are (a) sequential exploratory, (b) sequential explanatory, and (c) sequential transformative. Concurrent mixed methods designs–The three concurrent mixed methods designs identified by Creswell et al. (2003) are the following: (a) concurrent triangulation,.L or hidden populations (Denzin Lincoln, 1994), although by contrast qualitative approaches have often been methodologically weak in procedures for “mixing” qualitative and quantitative methods and data and for processing their inductively derived information (verbal evidence; Dreher, 1994; Gelo et al., 2008; Plano Clark et al., 2008). These limitations include weaknesses in precisely describing interrelationships that exist among two or more of inductively generated constructs or categories. Although such associations can be explored using visual case-ordered and predictor-outcome matrix methods that allow a crosstabulation of categorical information (Miles Huberman, 1994), nonetheless, these methods have lacked the capacity to reliably assess the strength of association among keyJ Mix Methods Res. Author manuscript; available in PMC 2011 December 11.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptCastro et al.Pagecategories or constructs, as can be accomplished with quantitative methods such as correlational analyses.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptEven among mixed methods studies, a common limitation has been the use of qualitative and quantitative approaches in a sequential temporal order, thus limiting the integration of both data forms under a unified process of data analysis (Bryman, 2007). Typically, focus group information has been obtained during Stage 1 (e.g., a pilot study) to develop or refine instruments and procedures, followed by Stage 2 (e.g., the “core study”) in which survey or other quantitative data are then collected (Creswell, 1994). Unfortunately, few studies have effectively integrated qualitative and quantitative approaches under a unified and fully integrative research design and data analytic plan (Bryman, 2007; Dreher, 1994; Hanson, Creswell, Clark, Petska, Creswell, 2005). Based on a decade of our pilot research, the IMM approach, as presented here, has been designed for a concurrent, integrative, and unified analysis of qualitative and quantitative data. It aims to incorporate the strengths of qualitative and quantitative approaches for conducting rigorous data analyses that meet scientific standards of reliable and valid measurement and analysis. Mixed Methods Design Approaches Sequential mixed methods designs–Creswell, Plano Clark, Gutmann, and Hanson (2003) classified mixed methods designs into two major categories: sequential and concurrent. In sequential designs, either the qualitative or quantitative data are collected in an initial stage, followed by the collection of the other data type during a second stage. In contrast, concurrent designs are characterized by the collection of both types of data during the same stage. Within each of these two categories, there can be three specific designs based on (a) the level of emphasis given to the qualitative and quantitative data (equal or unequal), (b) the process used to analyze and integrate the data, and (c) whether or not the theoretical basis underlying the study methodology is to bring about social change or advocacy (Creswell et al., 2003). In accord with this typology, the three types of sequential mixed methods designs are (a) sequential exploratory, (b) sequential explanatory, and (c) sequential transformative. Concurrent mixed methods designs–The three concurrent mixed methods designs identified by Creswell et al. (2003) are the following: (a) concurrent triangulation,.