2′-O-Methyl-p-thiouridynyl-(3′->5′)-2′-deoxyadenosine

Description:
2′-O-Methyl-p-thiouridynyl-(3′->5′)-2′-deoxyadenosine is an analog of the nucleoside uridine. It is a potent inhibitor of protein synthesis in cells, and has the potential to be used as a long-term treatment for tuberculosis. 2′-O-Methyl-p-thiouridynyl-(3′->5′)-2′-deoxyadenosine has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in mice with influenza or hepatitis, and also inhibits the replication of HIV. This drug may also have antibacterial properties due to its ability to inhibit bacterial DNA gyrase and topoisomerase IV. 2′-O-Methyl-p-thiouridynyl-(3′->5′)-2′-deoxyadenosine binds to an antigen on the surface of cells, activating them.