Product Name :
Hydroxy-PEG4-acid
Description:
Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
937188-59-5
Molecular Weight:
266.29
Formula:
C11H22O7
Chemical Name:
1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid
Smiles :
OCCOCCOCCOCCOCCC(O)=O
InChiKey:
UQWLGZFJGVEDCQ-UHFFFAOYSA-N
InChi :
InChI=1S/C11H22O7/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h12H,1-10H2,(H,13,14)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).{{α-Glucosidase} web|{α-Glucosidase} Glucosidase|{α-Glucosidase} Biological Activity|{α-Glucosidase} In stock|{α-Glucosidase} supplier|{α-Glucosidase} Autophagy} Hydroxy-PEG4-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.{{Zoliflodacin} medchemexpress|{Zoliflodacin} Anti-infection|{Zoliflodacin} Protocol|{Zoliflodacin} Formula|{Zoliflodacin} supplier|{Zoliflodacin} Epigenetic Reader Domain} |Product information|CAS Number: 937188-59-5|Molecular Weight: 266.29|Formula: C11H22O7|Chemical Name: 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid|Smiles: OCCOCCOCCOCCOCCC(O)=O|InChiKey: UQWLGZFJGVEDCQ-UHFFFAOYSA-N|InChi: InChI=1S/C11H22O7/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h12H,1-10H2,(H,13,14)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23910527 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|