Product Name :
Apicidin
Synonym :
Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]Cyclo(8-oxo-L-2-aminodecanoyl-1-metho xy-L-tryptophyl-L-isoleucyl-D-2-piperidinecarbonyl)Apicidin ia
Chemical Name :
CAS NO.:
183506-66-3
Molecular formula :
C34H49N5O6
Molecular Weight:
623.78 g/mol
Classification :
MedChemExpress Products > Research Chemicals >Fine Chemicals > Apicidin
Description:
Apicidin is a cyclic peptide that is structurally similar to the natural antibiotic apigenin. It has been shown to inhibit cancer cell proliferation and induce apoptosis in vitro. Apicidin has also been shown to be effective against squamous carcinoma, hl-60 cells, and mitochondrial membrane potential, as well as other types of cancer cells in vivo. Apicidin binds to the mitochondrial membrane and inhibits ATP synthesis by blocking the electron transport chain. This causes a decrease in cellular energy production and an increase in intracellular oxidative stress which leads to apoptosis.
Purity :
>98%
Specifications :
1 mg
Price.:
100
Price unit :
$
Inventory :
In stock
Related websites: https://www.medchemexpress.com
Popular product recommendations:
RHEB Rabbit mAb site
RbBP5 Rabbit mAb Epigenetic Reader Domain
CD147 Antibody: CD147 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 42 kDa, targeting to CD147. It can be used for WB,IHC-P,FC,IP assays with tag free, in the background of Human, Mouse.