Product Name :
Rosuvastatin D3
Description:
Rosuvastatin D3 (ZD 4522 D3) is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals.
CAS:
1133429-16-9
Molecular Weight:
484.56
Formula:
C22H28FN3O6S
Chemical Name:
(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(²H₃)methylmethanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Smiles :
[2H]C([2H])([2H])N(C1N=C(C(/C=C/[C@@H](O)C[C@@H](O)CC(O)=O)=C(N=1)C(C)C)C1C=CC(F)=CC=1)S(C)(=O)=O
InChiKey:
BPRHUIZQVSMCRT-UJWYGDJLSA-N
InChi :
InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1/i3D3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Rosuvastatin D3 (ZD 4522 D3) is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals.|Product information|CAS Number: 1133429-16-9|Molecular Weight: 484.{{Lenalidomide} MedChemExpress|{Lenalidomide} Ligands for E3 Ligase|{Lenalidomide} Biological Activity|{Lenalidomide} Formula|{Lenalidomide} manufacturer|{Lenalidomide} Autophagy} 56|Formula: C22H28FN3O6S|Chemical Name: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(²H₃)methylmethanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid|Smiles: [2H]C([2H])([2H])N(C1N=C(C(/C=C/[C@@H](O)C[C@@H](O)CC(O)=O)=C(N=1)C(C)C)C1C=CC(F)=CC=1)S(C)(=O)=O|InChiKey: BPRHUIZQVSMCRT-UJWYGDJLSA-N|InChi: InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1/i3D3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Resiniferatoxin} MedChemExpress|{Resiniferatoxin} Membrane Transporter/Ion Channel|{Resiniferatoxin} Technical Information|{Resiniferatoxin} Purity|{Resiniferatoxin} manufacturer|{Resiniferatoxin} Cancer} |Shelf Life: ≥12 months if stored properly.PMID:23543429 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|