Product Name :
Rituximab – 10mg/ml solution
Synonym :
Chemical Name :
CAS NO.:
174722-31-7
Molecular formula :
C6416H9874N1688O1987S44
Molecular Weight:
143.86 kg/mol
Classification :
MedChemExpress Products > Life Sciences > Antibodies > Monoclonal Antibodies > Rituximab – 10mg/ml solution
Description:
Rituximab is a glycosylated monoclonal antibody that binds to the CD20 cell surface protein which is widely expressed on B-cells. Through the binding of rituximabs Fc portion, the antibody-dependent cellular cytotoxicity pathway (ADCC) and the complement-dependent cytotoxicity (CDC) pathway are initiated, both leading to B-cell lysis (Chisari, 2021). In addition, direct apoptosis can be the result of the inhibition of various B-cell signalling pathways. Rituximab is used in targeted therapy for chronic lymphocytic leukaemia (CLL), non-Hodgkin lymphoma (NHL) and some non-cancer pathologies, such as, multiple sclerosis (Johnson, 2001).
Purity :
>98%
Specifications :
1 mg
Price.:
280
Price unit :
$
Inventory :
In stock
Related websites: https://www.medchemexpress.com
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