Product Name :
3-Hydroxy desloratadine
Synonym :
8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol3-HydroxydesloratadineSch 45581
Chemical Name :
CAS NO.:
119410-08-1
Molecular formula :
C19H19ClN2O
Molecular Weight:
326.82 g/mol
Classification :
MedChemExpress Products > Research Chemicals > 3-Hydroxy desloratadine
Description:
3-Hydroxy desloratadine is a metabolite of desloratadine. It is one of the metabolites that can be formed from the drug in vivo, after oral administration. 3-Hydroxy desloratadine has been shown to be an active metabolite in vitro and in vivo, with linear calibration curves (R2>0.99) for both human liver and human plasma samples. The metabolic profile of 3-hydroxy desloratadine is similar to that of desloratadine, including inhibition of cytochrome P450 enzymes and glucuronidation by glucuronidases. In vitro studies have shown that 3-hydroxy desloratadine is not a substrate for CYP2D6 or CYP3A4, but it may inhibit CYP1A2 and CYP2C19. It has also been shown to be a substrate for UGT1A6 and UGT2B7.
Purity :
>98%
Specifications :
500 μg
Price.:
166
Price unit :
$
Inventory :
Out of stock
Related websites: https://www.medchemexpress.com
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