Product Name :
GW 441756
Description:
GW-441756 is a potent inhibitor of TrkA (IC50 = 2 nM). Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma.
CAS:
504433-23-2
Molecular Weight:
275.30
Formula:
C17H13N3O
Chemical Name:
(3Z)-3-[(1-methyl-1H-indol-3-yl)methylidene]-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one
Smiles :
CN1C=C(/C=C2\C(=O)NC3=CC=CN=C\23)C2=CC=CC=C12
InChiKey:
NXNQLECPAXXYTR-LCYFTJDESA-N
InChi :
InChI=1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Anti-Mouse CD28 Antibody} medchemexpress|{Anti-Mouse CD28 Antibody} CD28|{Anti-Mouse CD28 Antibody} Biological Activity|{Anti-Mouse CD28 Antibody} Data Sheet|{Anti-Mouse CD28 Antibody} supplier|{Anti-Mouse CD28 Antibody} Epigenetics}
Shelf Life:
≥360 days if stored properly.{{Inosine} site|{Inosine} Endogenous Metabolite|{Inosine} Protocol|{Inosine} References|{Inosine} supplier|{Inosine} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23819239
Additional information:
GW-441756 is a potent inhibitor of TrkA (IC50 = 2 nM). Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma.|Product information|CAS Number: 504433-23-2|Molecular Weight: 275.30|Formula: C17H13N3O|Chemical Name: (3Z)-3-[(1-methyl-1H-indol-3-yl)methylidene]-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one|Smiles: CN1C=C(/C=C2\C(=O)NC3=CC=CN=C\23)C2=CC=CC=C12|InChiKey: NXNQLECPAXXYTR-LCYFTJDESA-N|InChi: InChI=1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|