Product Name :
Methylophiopogonanone A
Description:
Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties.
CAS:
74805-92-8
Molecular Weight:
342.34
Formula:
C19H18O6
Chemical Name:
(3R)-3-[(2H-1,3-benzodioxol-5-yl)methyl]-5,7-dihydroxy-6,8-dimethyl-3,4-dihydro-2H-1-benzopyran-4-one
Smiles :
CC1C2OC[C@@H](CC3C=C4OCOC4=CC=3)C(=O)C=2C(O)=C(C)C=1O
InChiKey:
BXTNNJIQILYHJB-GFCCVEGCSA-N
InChi :
InChI=1S/C19H18O6/c1-9-16(20)10(2)19-15(17(9)21)18(22)12(7-23-19)5-11-3-4-13-14(6-11)25-8-24-13/h3-4,6,12,20-21H,5,7-8H2,1-2H3/t12-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Benzbromarone} medchemexpress|{Benzbromarone} Immunology/Inflammation|{Benzbromarone} Protocol|{Benzbromarone} References|{Benzbromarone} manufacturer|{Benzbromarone} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties.|Product information|CAS Number: 74805-92-8|Molecular Weight: 342.34|Formula: C19H18O6|Chemical Name: (3R)-3-[(2H-1,3-benzodioxol-5-yl)methyl]-5,7-dihydroxy-6,8-dimethyl-3,4-dihydro-2H-1-benzopyran-4-one|Smiles: CC1C2OC[C@@H](CC3C=C4OCOC4=CC=3)C(=O)C=2C(O)=C(C)C=1O|InChiKey: BXTNNJIQILYHJB-GFCCVEGCSA-N|InChi: InChI=1S/C19H18O6/c1-9-16(20)10(2)19-15(17(9)21)18(22)12(7-23-19)5-11-3-4-13-14(6-11)25-8-24-13/h3-4,6,12,20-21H,5,7-8H2,1-2H3/t12-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (292.11 mM; Need ultrasonic).{{Telotristat ethyl} medchemexpress|{Telotristat ethyl} Metabolic Enzyme/Protease|{Telotristat ethyl} Purity & Documentation|{Telotristat ethyl} In Vitro|{Telotristat ethyl} supplier|{Telotristat ethyl} Autophagy} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32108537 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Methylophiopogonanone A (MO-A; 10 μmol/L) significantly decreases apoptosis and cleaved caspase-3 expression, elevated the Bcl-2/Bax ratio and restored NO production. Pretreatment with Methylophiopogonanone A (MO-A) markedly increases the activation of PI3K/Akt/eNOS pathway in H9C2 cells subjected to H/R, and the protective effects of MO-A are abolished in the presence of the PI3K inhibitor wortmannin (100 nmol/L).|In Vivo:|Methylophiopogonanone A (MO-A;10 mg/kg/d, po) for 2 weeks) protects cardiac function following myocardial I/R injury.|Products are for research use only. Not for human use.|