Also fire at any future time points when the trigger make
Also fire at any future time points when the trigger make this transition; in other words, an occasion can fire many occasions in the course of a simulation if its trigger situation makes the transition from ” false” to ” true” greater than as soon as. A crucial question is no matter whether an event can fire prior to, or at, initial simulation time, i.e t 0. The answer is no: an event can only be triggered quickly following initial simulation time i.e t 0. The optional sboTerm attribute on Trigger: As with all SBML elements derived from SBase, Trigger inherits the optional attribute sboTerm of kind sboTerm (see Sections three..9 and five). When a worth is provided to this attribute, it should be a valid term representing a mathematical expression (i.e a term chosen in the SBO:0000064, “mathematical expression” hierarchy). The formula within the Trigger’s math expression really should have an “is a” relationship with the SBO term, along with the term really should capture most precise (narrow) meaning in the mathematical formula of PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/23153055 the trigger. four.four.three DelayAs shown in Figure 22, an Event object can contain an optional delay element of class Delay. The Delay is derived from SBase and contains a mathematical formula stored in math. The formula is utilized to compute the length of time in between when the event has fired and when the event’s assignments (see below) are truly executed. If no delay is present on a provided Event, a time delay of zero is assumed.Pefa 6003 Author Manuscript Author Manuscript Author Manuscript Author ManuscriptJ Integr Bioinform. Author manuscript; accessible in PMC 207 June 02.Hucka et al.PageThe expression within the Delay object’s math element should be evaluated at the time the event is fired. The expression ought to usually evaluate to a nonnegative quantity (otherwise, a nonsensical predicament could arise where an event is defined to fire just before it really is triggered!). Units of delay expressions: The units from the numerical worth computed by a Delay instance’s math expression really should match the model’s units of time (meaning the definition in the ” time” units in the model; see Section 4.four.three). Note that, as in other cases of MathML expressions in SBML, units will not be predefined or assumed. As discussed in Section three.four literal numbers (i.e numbers enclosed in MathML cn elements) or expressions containing only literal numbers andor Parameter objects without having declared units, are regarded to have unspecified units. In such instances, the correspondence in between the required units as well as the (unknown) units of your Delay math expression can’t be established, and though such expressions are usually not considered inconsistent, all that will be assumed by model interpreters (regardless of whether application or human) is the fact that the units may be constant. The following Event instance fragment helps illustrate this:Author Manuscript Author Manuscript Author Manuscript Author ManuscriptNote the ” cn 0 cn” inside the mathematical formula has no specified units. The model is just not invalid because of this, but a recipient from the model may justifiably be concerned about what ” 0″ seriously signifies. (Ten seconds What when the international units of time around the model had been changed from seconds to milliseconds Would the modeler keep in mind to modify ” 0″ to ” 0 000″) As discussed elsewhere, leaving units unspecified may avoid software tools from performing full validation along with other beneficial operations for example worldwide unit conversions. A greater approach should be to prevent literal numbers and as an alternative use an strategy for instance defining a parameter with declared units, as within the following mo.