Antioxidant defense which is an important removal mechanism of reactive oxygen species. Superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) constitute a part of the antioxidant system that protects…
ndividuals by analyzing the distribution and clustering of hundreds and
Terials and MethodsAll restriction enzymes were obtained from New England Biolabs (Frankfurt/Main, Germany) or Fermentas (St. Leon-Rot, Germany). Oligonucleotide primers were synthesized by MWG (Ebersberg, Germany). All chemicals were of…
st statistic reflects a biologist's view that a gene with a greater fold change than other genes is potentially the more interesting one. Also, given two genes with the same…
r family. In addition to transcription factors, the regulated genes were mainly involved in several different metabolic processes relating to hormones, secondary substances, carbohydrates, lipids, and amino acids. Up-regulated genes…
dentify relevant interacting proteins and novel candidates in signal transduction cascades. Acknowledgements This work was supported by the Netherlands Organization for Scientific Research, Grant No. 014-80-008. We thank R. Barstead…
At the insect flight circuit is formed during pupal development . Therefore, the MedChemExpress 69-25-0 effect of blocking synaptic activity in serotonergic neurons during pupal development and in adults was…
He modified SL2-B. Solid line is PS-modified SL2-B, dashed line is BTZ043 unmodified SL2-B, and dotted line is scrambled sequence. doi:10.1371/journal.pone.0050964.gAntiproliferative Activity of Aptamer on CancerFigure 6. Effect of PS-modified…
est in them owing to their beneficial metabolic effects on glucose homeostasis, food intake, insulin sensitivity and body weight. SCFAs, such as acetate, propionate and butyrate, are produced by gut…
assays, we also cloned and transduced three gRNA's that target the non-essential and non-coding Rosa26 locus. To assess the efficacy of our CRISPR system, we purified GFP+ populations from cell…