MMPs are proteolytic enzymes, whereas their activity is regulated by TIMPs as their endogenous inhibitors. Hence, the balance of MMPs/TIMPs expression is emerging as crucial regulator of myocardial transforming
After the clipping of the left renal artery, this is also a product of renovascular hypertension that has a substantial activation of the renin-angiotensinaldosterone system. Angiotensin II (Ang II), the…