Ubiquitin-mediated degradation of mitotic B-sort cyclins by the anaphase-marketing complicated/cyclosome (APC/C) was initial described in budding yeast [21,22]
To establish whether cdr2 protein is degraded by the proteasome, we examined the effect of MG132, a 1047634-65-0 biological activityproteasome inhibitor, on amounts of T7cdr2 in HEK293 cells. MG132 remedy…